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What is in the FB3® formula?

FB3® is a patent-pending blend of three synergistic botanicals preventing excess dietary fat absorption:

  1. Coleus forskohlii (Briq.) root extract standardized for10% diterpene forskolin.
  2. Salacia reticulata (Wight.) root and leaves extract standardized for 10% polyphenols (salacinol, kotalanol, and mangiferin) and α-glucosidase inhibition IC50 >250 mcg/ml.
  3. Sesamum indicum (L.) seed extract standardized for 70% lignan sesamin and not less than 15% other lignans, e.g. sesamolin, episesamin.

Is FB3® safe?

The preclinical and clinical studies published on FB3 and its components [Journal of Functional Foods 18(2015) 994-1001 and Nutrients 2015, 7, 9508-9522], showed no safety concerns or subjective and objective complaints from participants in the studies conducted for 6 and 12 weeks respectively.

The lead component of FB3®, C. forkohlii, has obtained the High Quality Certification from Japan Health Food and Supplement Association. This certificate was awarded after evaluation of the FB3® C. forskohlii safety data, green-solvents extraction technology and the peer-reviewed published clinical efficacy data. The regulatory evaluation process took over 1.5 years to complete and attests to high quality of the FB3® formula.

The natural ingredients used in FB3® are selected from world-renowned companies and represent quality and tradition supported by science, sustainability, and social responsibility. All products are researched and approved by American Medical Holdings Inc.

Our products, practices, and procedures meet or exceed all industry and government standards of excellence for quality assurance, safety assurance, and potency. Good Manufacturing Practices (GMPs) are used throughout our manufacturing process. GMPs are comprehensive manufacturing standards established by the United States Pharmacopoeia for the production of pharmaceuticals.

What is in the FB3® formula?

Based on a 2015 published peer-review study the formula of FB3 is safe, effective and synergistic method preventing excess body fat, by limiting gastorintestinal dietary fat absorption. [Journal of Functional Foods 18(2015) 994-1001]. Another 2015 published clinical study on FB3 indicates that it may improve insulin sensitivity in obese individuals which regulates lipid metabolism in the body. [Nutrients 2015, 7, 9508-9522] The cited clinical studies also show FB3 led to diminished food cravings and caloric intake.

What is the effective dose of FB3®

For optimal efficacy, FB3 should be administered in three 415 mg doses a day. Each dose should be used 30 minutes before a meal.

For weight-management maintenance, FB3 can be taken as a single daily dose of 415 mg, 30 minutes before breakfast.

FB3 is best administered orally – in capsules, tablets, healthy foods, e.g. nutritional bars, wafers, water-dispersible powders, or functional beverages. Based on research and other scientific literature, FB3 can be used for a 12-week period, supported by lifestyle and nutritional modification.

How soon may I expect health benefits with FB3?

The promise of FB3 is not in an immediate weight loss, but in a gradual deactivation (not inhibition) of the endocannabinoid system (ECS), leading to improvement of metabolic functions and fatty acid oxidation, putting the individual on the path to gradual regaining healthy body composition and loss of both body fat and body weight.

What is the understanding of FB3® health benefits?

In the human diet, there are three macronutrients:  carbohydrates, protein and fat. When balanced and from healthy sources, such a diet can keep individuals mostly healthy. When out of balance, weight issues and other health-related conditions may begin to surface. Unhealthy fats are saturated fats, found in red meat, poultry and full-fat dairy. Trans-fats, recently banned by the FDA, are also very unhealthy. In addition, the new evidence emerges that saturated fat of animal origin, which is an energy “white” storage fat, may not necessarily be the only culprit in obesity but is joined by certain vegetable oils, e.g. safflower, sunflower, corn, soy and peanut oils, which are rich in n-6 linoleic acid and are omnipresent in our daily processed food. Each of us has a natural protective metabolic mechanism against obesity which can be overwhelmed when the body is frequently barraged by food. When we arrive to that turn-around point the body can respond with misguided pathological mechanisms, which in time become the cause of obesity and/or type 2 diabetes mellitus. One such mechanism is due to excess dietary fatty acids that activates endocannabinoid system (ECS), gradually incapacitate hepatocytes (liver cells), and compromise one of the major functions of the liver, oxidation and utilization of fat for energy. A liver burdened with accumulated fat clinically is referred to as non-alcoholic fatty liver disease (NAFLD).

Based on the 2015 peer-review preclinical and clinical studies of FB3®, this proprietary dietary supplement when combined with the healthy diet and life-style may prevent excess body fat build-up by interfering with the excess dietary fat absorption. The unabsorbed dietary fat is ultimately eliminated from the body, and the cumulative effect of FB3® and the healthy diet including omega-3 fatty acids may be summarized as “Good Fat in, Excess Fat out” (see Nutracos May 2015 in article “Good Fat In, Excess Fat Out”).